Multivalent display of pendant pro-apoptotic peptides increases cytotoxic activity
نویسندگان
چکیده
منابع مشابه
Multivalent display of the antimicrobial peptides BP100 and BP143
Carbohydrates are considered as promising templates for the display of multiple copies of antimicrobial peptides. Herein, we describe the design and synthesis of chimeric structures containing two or four copies of the antimicrobial peptides KKLFKKILKYL-NH(2) (BP100) and KKLfKKILKYL-NH(2) (BP143) attached to the carbohydrate template cyclodithioerythritol (cDTE) or α-D-galactopyranoside (Galp)....
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ژورنال
عنوان ژورنال: Journal of Controlled Release
سال: 2015
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2015.01.013